Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels

Jeffrey D Fineberg, David M Ritter, Manuel Covarrubias

J Gen Physiol. 2012 Nov;140(5):513-27. doi: 10.1085/jgp.201210869.

A study showing that experimentally different ion channels inactivate via different mechanisms. The role of these inactivation mechanisms was then determined in an model neuron.

https://rupress.org/jgp/article/140/5/513/43084/Modeling-independent-elucidation-of-inactivation

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Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons

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Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury