Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons

Written By David Ritter

David M Ritter, Cojen Ho, Michael E O'Leary, Manuel Covarrubias

J Physiol. 2012 Jan 1;590(1):145-61. doi: 10.1113/jphysiol.2011.218560. Epub 2011 Nov 7.

Work shows that’s a specific potassium channel, Kv3.4, is important for regulating the action potential (electrical signals) in pain-sensing neurons.

https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/jphysiol.2011.218560

David Ritter
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A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction
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Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels